Affinity DataKi: 0.0340nMAssay Description:Antagonist activity at full length human H4R expressed in HEK293 cells assessed as reversal of forskolin-induced cAMP production by CRE-beta-lactamas...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine receptor H4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine receptor H4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
TargetHistamine receptor H4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.920nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-Histamine from human histamine 4 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -12.3kcal/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human recombinant histamine H4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Antagonist activity at full length human H4R expressed in HEK293 cells assessed as reversal of forskolin-induced cAMP production by CRE-beta-lactamas...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.51nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.56nMAssay Description:Antagonist activity at full length human H4R expressed in HEK293 cells assessed as reversal of forskolin-induced cAMP production by CRE-beta-lactamas...More data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Agonistic activity at histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to histamine H4 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]histamine from human full-length histamine H4 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-histamine from full length human H4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair